The Cardiology Unit continues to develop its research program in association with key areas of clinical service.
In addition to the link with the University of Melbourne Department of Medicine – Western Precinct, collaborative ties with Victoria University, Monash University and the Baker Institute were strengthened. The unit looks forward to ongoing increased growth and research output in the year to come.
Current active clinical trials:
ARTEMIS: Effects of ziltivekimab versus placebo on cardiovascular outcomes in patients with acute myocardial infarction Commercial Sponsor: Novonordisk Principal Investigator: Prof William Chan
EDICT-HF: Early Discharge to Clinic-Based Therapy of Patients Presenting With Decompensated Heart Failure Investigator Initiated Sponsor: Western Health Principal Investigator: A/Prof Ben Costello
GOAL-ASIA: Guideline Oriented Approach to Lipid Lowering In Asia-Pacific Investigator Initiated Sponsor: Monash University Principal Investigator: Dr. Omar Al-Mukhtar
PREVAIL: Obicetrapib and Cardiovascular Outcomes: A Placebo-Controlled, Double-Blind, Randomized Phase 3 Study to Evaluate the Effect of 10 mg Obicetrapib in Participants With Atherosclerotic Cardiovascular Disease (ASCVD) Who are Not Adequately Controlled Despite Maximally Tolerated Lipid-Modifying Therapies. Commercial Sponsor: NewAmsterdam Pharma BV, The Netherlands Principal Investigator: Dr Ben Costello
RESTORE MI: Restoring Microcirculatory Perfusion in ST-Elevation Myocardial Infarction Investigator Initiated Sponsor: University of Sydney Principal Investigator: A/Prof William Chan
SOS-AMI: Selatogrel Outcome Study in suspected Acute Myocardial Infarction (SOS-AMI). A multi-centre, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of self-administered subcutaneous selatogrel for prevention of all-cause death and treatment of acute myocardial infarction in subjects with a recent history of acute myocardial infarction Commercial Sponsor: Viatris Innovation GmbH Principal Investigator: Dr Ben Costello
Page last updated November 2025
